Dosing of CoQ10

Suggested use:  Take 1 to 2 capsules per day with or without food.

Contraindications:  means that you should not take this product if you are taking one of the listed products below.  You should check with your medical provider prior to taking this product if you are taking any of the listed medications.

• Medications for cancer (Chemotherapy) interacts with COENZYME Q10 (CoQ10).  CoQ10 is an antioxidant and there is some concern that antioxidants might decrease the effectiveness of some medications used for cancers.

• Medications for high blood pressure (Antihypertensive drugs) can interact with CoQ10.  CoQ10 seems to decrease blood pressure. Taking CoQ10 along with medications for high blood pressure might cause your blood pressure to go too low.  Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.

• Warfarin (Coumadin) interacts with CoQ10.  Warfarin (Coumadin) is used to slow blood clotting. There is evidence that CoQ10 helps improve clotting factor within the blood.  By helping the blood clot, coenzyme Q-10 might decrease the effectiveness of warfarin (Coumadin). Decreasing the effectiveness of warfarin (Coumadin) might increase the risk of clotting. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.

Physiology of CoQ10

Coenzyme Q10 is the spark plug that ignites the body’s engine by jump-starting energy production within all cells. The body then uses that cellular energy to fuel vital biological processes. CoQ10 is present in every cell of your body and it is essential for sustaining a wide range of healthy biological functions. 

One of CoQ10’s pivotal roles in the body is energy metabolism.  The major part of cellular ATP (energy) production happens within the inner membrane of the mitochondria, the powerhouse of the cell.  CoQ10 is a critical component of the electron transfer chain in mitochondrial respiration.  Due to the vital role it plays in the production of cellular energy, small changes in CoQ10 levels within the mitochondria have been shown to have significant effects on the rate of cellular respiration.  Thus, a lack of CoQ10 may lead to declining energy levels and decreased stamina.

CoQ10 in the Ubiquinol form plays a key role as an antioxidant by neutralizing free radicals and preventing oxidative damage to the body’s cells, proteins, lipids, and DNA.  CoQ10 can also regenerate the active forms of vitamin E and vitamin C, some of the most powerful water-soluble antioxidants. 

• It is also known as Q10, vitamin Q10, ubiquinone, or ubidecarenone.
• Helps reduce musculoskeletal pain caused by Statin cholesterol reducing medicines
• Helps with quick recover from vigorous exercise
• Helps treat high blood pressure and various types of heart disease
• Helps enhance immune system function
• Helps provide energy boosts for people dealing with fatigue
• Help reduce high cholesterol levels in the blood
• Helps stabilize blood sugar levels of people
• Helps in the treatment of cancer or the protection of organs from toxic chemotherapy drugs
• Help treat gum disease
• Helps slow down the progression of dementia
• Helps increase sperm count and motility
• Helps in preventing and treating migraine headaches

Absorption & normal levels of CoQ10:

• C-max/T-max: approximately 6 hours. C-max is a term used that refers to the maximum (or peak) serum concentration that a product or drug achieves in. This is Important to know since to help prevent taking additional doses within that time frame.
• Half-life: about 33 hours.  Half-life is defined as the time required for the product or drug to decrease by half.

• Normal blood levels range from 0.40 to 1.91 μmol/L in healthy adults.

Side Effects CoQ10

Coenzyme Q10 can cause some mild side effects including an upset stomach, nausea, vomiting, and diarrhea when taken at high doses. Just like some drugs, foods, and supplements, some people may be allergic to it and should avoid taking it if It can cause allergic skin rashes.

DO NOT take CoQ10 when undergoing Chemotherapy for cancer and being treated with alkylating agents.   By taking CoQ10, it can lower the effectiveness of chemotherapy drugs.

High blood pressure or low blood pressure: Coenzyme Q10 might lower blood pressure. It can increase the effects of medications used to lower blood pressure. Discuss your use of coenzyme Q10 with your healthcare provider if you have blood pressure problems.

Surgery: Coenzyme Q10 might interfere with blood pressure control during and after surgery. Stop using coenzyme Q10 at least two weeks before a scheduled surgery.

Warning: If you are pregnant, nursing or on prescription medications, consult your doctor before use.  Do not use if safety seal is broken or missing.  Discontinue use if adverse reactions occur.  Close tightly and keep out of reach of children.

A serious allergic reaction can occur when consuming any food, nutritional supplement, or medicine.   If you experience any of the below side effects seek immediate medical attention.

• Rash
• Hives
• Itching/swelling: especially of the face, tongue, and/or throat
• Severe dizziness
• Trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your medical provider.

Disclaimer

Nutritional supplements are classified as a food by the US Food and Drug Administration (FDA). Supplements do not require the same rigorous testing, review and approval that drugs are required to go through. Therefore, the statements contained in this document regarding CoQ10 have not been reviewed and approved by the FDA. However, significant research has been done on this product by many universities, public and private business. We at 5-Point Wellness, LLC desire to share information about CoQ10, in order to educate our clientele to make well informed decisions for themselves.